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Amazon.com Review
An Amazon Best Book of June 2018: Heredity is a lot more complex than most people think. In She Has Her Mother’s Laugh, New York Times columnist Carl Zimmer dives deep into the ways that we pass along our genetic inheritance. Through history, science, and a boatload of personal curiosity (the book originated from questions he had regarding his own child, and he had his entire genome mapped in the process of writing it), Zimmer seeks to retell the story of heredity in broader and more inclusive terms than the ones we’re used to hearing. For example, who we become is determined by our ancestors’ genes, yes; but it is also a product of our own cells—for one cell can contribute to millions of future cells. How we treat ourselves, what we learn, and even how we feel, eventually contributes to our hereditary future. The forces at work are myriad, mostly unseen, and subject to variables that we barely understand. Zimmer is trying to help us here, to teach us, and in doing so he succeeds in entertaining us as well. --Chris Schluep, Amazon Book Review
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Praise for She Has Her Mother’s Laugh“Extraordinary...This book is Zimmer at his best: obliterating misconceptions about science with gentle prose. He brings the reader on his journey of discovery as he visits laboratory after laboratory, peering at mutant mosquitoes and talking to scientists about traces of Neanderthal ancestry within his own genome. Any fan of his previous books or his journalism will appreciate this work. But so, too, will parents wishing to understand the magnitude of the legacy they’re bequeathing to their children, people who want to grasp their history through genetic ancestry testing and those seeking a fuller context for the discussions about race and genetics so prevalent today.”—The New York Times Book Review“Magisterial...In Zimmer’s pages, we discover a world minutely threaded with myriad streams of heredity flowing in all directions, in variegated patterns and different registers.”—The Atlantic"The strength of [She Has Her Mother's Laugh]...is its combination of accuracy, journalistic clarity and scientific authority...If the science doesn’t matter to you now, it will soon."—The Washington Post“Zimmer is careful and well-informed... Acquired traits can be inherited. Biological time can turn backward. And monsters are real.”—Wall Street Journal"Carl Zimmer’s magnum opus, probing myriad strands of science through the prism of decadeslong, stellar reporting, and a leading contender as the most outstanding nonfiction work of the year…a lush, enthralling book that transforms the reader with its insights.”—Minneapolis Star-Tribune“Expansive, engrossing, and often enlightening... Zimmer takes readers on a tale through time and technology, from the inbred Holy Roman Empire to the birthplace of American eugenics to the Japanese lab where scientists are reprogramming skin cells into eggs and sperm."—Wired“A chronicle of timeless values, and the permanent importance of bonds of kinship and the passing of generations in human culture. It is also a stark caution against human hubris, as the early decades of hereditary science show just how much damage science can cause when it’s poorly done and unethically applied. Finally, it is a wondrous exposé of the rapid-fire results and advances being made in 21st-century genetics, and the social and cultural consequences that they might unleash.”—National Review"Nuanced, entertaining and balances eloquent story-telling with well-researched science... Anyone interested in their path through history, and what they may hand on, will find much to excite them... She Has Her Mother's Laugh is, as promised, a showcase of the powers, perversions and potential of what we truly gain from our past and pass on to our future.” —New Scientist“A beguiling narrative… Whatever your views on the power of genes versus other forms of heredity, you will be in for a few surprises.”—Nature "Into this zeitgeist enters Carl Zimmer’s most enjoyable new book, She Has Her Mother’s Laugh, with a sweeping overview of the history of our understanding of heredity… [He is] one of the best science journalists of our time.”—Science“A magnificent work...Journalist Zimmer masterfully blends exciting storytelling with first-rate science reporting. His book is as engrossing as it is enlightening.”—Publishers Weekly (starred review) “A thoroughly enchanting tour of big questions, oddball ideas, and dazzling accomplishments of researchers searching to explain, manipulate, and alter inheritance.”—Kirkus Reviews (starred review)“A wide-ranging and eye-opening inquiry into the way heredity shapes our species.” —Booklist (starred review)“Zimmer’s latest offers a comprehensive look at all aspects of heredity in readable and accessible text for anyone interested in the topic.” —Library Journal“This massive, multifaceted account of heredity's history and possible future illuminates the subject as something much more complex than genes passed from generation to generation.”—Shelf Awareness“A story filled with palace intrigue and breathtaking innovation.”—O, The Oprah Magazine"This is clearly Zimmer’s best book. It’s an opus in which he goes through the entire history of genetics and epigenetics, and writes about getting his own genome sequenced too. She Has Her Mother’s Laugh is one of the best books ever written about genetics, along with Siddhartha Mukherjee’s The Gene. They’re the two bookends."—Science Friday, Best Science Books of 2018"A rich and wide-ranging exploration of the mysterious science that makes us, somehow, who we are.”—Jamie Green, Thrillist's Best Books of 2018“No one unravels the mysteries of science as brilliantly and compellingly as Carl Zimmer, and he has proven it again with She Has Her Mother’s Laugh—a sweeping, magisterial book that illuminates the very nature of who we are.” —David Grann, author of Killers of the Flower Moon and The Lost City of Z “She Has Her Mother's Laugh is at once far-ranging, imaginative, and totally relevant. Carl Zimmer makes the complex science of heredity read like a novel, and explains why the subject has been--and always will be—so vexed.”—Elizabeth Kolbert, author of Pulitzer Prize-winning The Sixth Extinction “Humans have long noticed something remarkable, namely that organisms are similar but not identical to their parents—in other words, that some traits can be inherited. From this observation has grown the elegant science of genetics, with its dazzling medical breakthroughs. And from this has also grown the toxic pseudosciences of eugenics, Lysenkoism and Nazi racial ideology. Carl Zimmer traces the intertwined histories of the science and pseudoscience of heredity. Zimmer writes like a dream, teaches a ton of accessible science, and provides the often intensely moving stories of the people whose lives have been saved or destroyed by this topic. I loved this book.” —Robert Sapolsky, Stanford University, author of Behave“She Has Her Mother's Laugh is a masterpiece—a career-best work from one of the world's premier science writers, on a topic that literally touches every person on the planet.”—Ed Yong, author of I Contain Multitudes“Nobody writes about science better than Carl Zimmer. As entertaining as he is informative, he has a way of turning the discoveries of science into deeply moving human stories. This book is a timely account of the uses and misuses of some of the science that directly impact our lives today. It is also a career moment by one of our most important and graceful writers. Here is a book to be savored.”—Neil Shubin, University of Chicago, author of Your Inner Fish“Zimmer is a born story-teller. Or is he an inherited story-teller? The inspiring and heartbreaking stories in She Has Her Mother’s Laugh build a fundamentally new perspective on what previous generations have delivered to us, and what we can pass along. An outstanding book and great accomplishment.”—Daniel Levitin, author of This is Your Brain on Music and The Organized Mind“One of the most gifted science journalists of his generation, Carl Zimmer tells a gripping human story about heredity from misguided notions that have caused terrible harm to recent ongoing research that promises to unleash more powerful technologies than the world has ever known. The breadth of his perspective is extraordinarily compelling, compassionate, and valuable. Please read this book now.” —Jennifer Doudna, UC Berkeley, coauthor of A Crack in Creation“Carl Zimmer lifts off the lid, dumps out the contents, and sorts through the pieces of one of history's most problematic ideas: heredity. Deftly touching on psychology, genetics, race, and politics, She Has Her Mother's Laugh is a superb guide to a subject that is only becoming more important. Along the way, it explains some remarkably complicated science with equally remarkable clarity—a totally impressive job all around.” —Charles C. Mann, author of 1491: New Revelations of the Americas Before Columbus“Carl Zimmer is not only among my favorite science writers—he’s also now responsible for making me wonder why there is more Neanderthal DNA on earth right now than when Neanderthals were here, and why humanity is getting taller and smarter in the last few generations. She Has Her Mother’s Laugh explains how our emerging understanding of genetics is touching almost every part of society, and will increasingly touch our lives.” —Charles Duhigg, author of Smarter Faster Better and The Power of Habit “With this book, Carl Zimmer rises from being our best biological science writer to being one of our very best non-fiction writers in any field, period.”—Kevin Padian, professor of integrative biology, UC Berkeley“How every characteristic—from genes to personality—is passed down from one generation to the next is one the most fundamental, complex, misunderstood and misused enigmas of biology. In this beautifully written, heartfelt and enjoyable masterpiece, Zimmer weaves together history, autobiography and science to elucidate the mysteries of heredity and why we should care. I couldn’t put this book down, and can’t recommend it too highly.” —Daniel E. Lieberman, Harvard University, author of The Story of the Human Body“She Has Her Mother’s Laugh is at once enlightening and utterly compelling. Carl Zimmer weaves spellbinding narrative with luminous science writing to give us the story of heredity, the story of us all. Anyone interested in where we came from and where we are going—which is to say everyone—will want to read it.”—Jennifer Ackerman, author of The Genius of Birds and Chance in the House of Fate“Traversing time and societies, the personal and the political, the moral and the scientific, She Has Her Mother's Laugh takes readers on an endlessly mesmerizing journey of what it means to be human. Carl Zimmer has created a brilliant canvas of life that is at times hopeful, at times horrifying, and always beautifully rendered. I could hope for no better guide into the complexities, perils, and, ultimately, potential of what the science of heredity has in store for the world.” —Maria Konnikova, author of The Confidence Game “With his latest work, Zimmer has assured his place as one of the greatest science writers of our time. She Has Her Mother’s Laugh is an extraordinary exploration of a topic that is at once familiar and foreign, and touches every one of us. With the eloquence of a poet and the expertise of a scientist Zimmer has created a nonfiction thriller that will change the way you think about your family, those you love, and the past and future.” —Brian Hare, Duke University, coauthor of The Genius of Dogs“Zimmer offers a compelling look at genetics...You will leave this book realizing how little we know about how we come to be.”—Bitch Media
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Product details
Hardcover: 672 pages
Publisher: Dutton; First Edition edition (May 29, 2018)
Language: English
ISBN-10: 9781101984598
ISBN-13: 978-1101984598
ASIN: 1101984597
Product Dimensions:
6.4 x 2 x 9.5 inches
Shipping Weight: 2.1 pounds (View shipping rates and policies)
Average Customer Review:
4.3 out of 5 stars
70 customer reviews
Amazon Best Sellers Rank:
#12,284 in Books (See Top 100 in Books)
Public understanding of heredity has profound consequences for many dimensions, including research funding, toxicology, medicine, regulation, and even warfare. For example, warped views of heredity fueled ideologies that killed tens of millions in WWII and more recently has funneled the bulk of precious research dollars into the ridiculously shallow box of genetic causation for today's public health crises. Because our limited views of heredity need a sweeping update, I give this book 5 stars for its scope, ambition, and exquisite quality of execution. It takes us a solid step in the right direction, and will greatly enrich public dialogue.Sadly, the book does falter in one key area—Zimmer's weak treatment of epigenetic inheritance. First, he mistakenly calls it a "new flavor of Lamarckism," which is incorrect. The research in this area largely involves direct exposures to early germ cells, and the heritable consequences thereof, and not with some fluffy idea about "acquired characteristics" wending their way into the germline. Moreover, while Zimmer briefly mentions nutrition, plasticizers, and pesticides as exposures that may influence nongenetic germline-borne heredity, he altogether ignores the compelling and deeply troubling evidence of generational pathology caused by the toxic pregnancy drug diethylstilbestrol (DES). How he could have overlooked heritable consequences of the greatest medical catastrophe of our age, yet decide to devote 2/3 of a page to an uber-skeptic like Kevin Mitchell is beyond me. But fear not, good readers, the other 99.99% of the book is outstanding and deserves your attention.
Herr Zimmer does it again !- I have been his fan since his earlier book on E coli .Average reader without Biology background need not get intimidated by length of the book . The book reads like a well crafted Novel.He explains complex concepts in very simple words interspersed with human interest stories.This book covers new material and has a different approach compared to Dr. Siddhartha Mukherjee's popular book .The extensive Bibliography is helpful for further reading.This work represents Science writing at its Best.
My rating of the book is 4 out of 5. It is not quite clear for what group of people it was written: a little too complex and lacking illustrations for generalists and a little too generalized for experts. I agree with the reviewer who suggests that a potential purchaser/reader might want to look at some parts of an electronic version to be able to form an opinion if the book is for him/her. What I found most surprising in the existing reviews is that nobody seems to address the content of Part V, the development and usage of CRISPR and related technology. It has the potential of changing humanity for better or for worse and it is up to humans to decide which direction to take, in a general way as the decision or lack of it to control earth’s surface temperature. It is a subject that should be studied and discussed much more by the general public that can learn about it in this book.
I'm not a professional academic - purchased based on an amazing consensus of notable biologists recommends. I was not disappointed other than the fact that it finally ended in Chapter 19. Kept wanting more. To me it is the history and future of life on our planet. I'm in my late 60's. The ground Zimmer covers in his historical narratives struck me personally as amazing. Such a diverse accounting of past personnages. I figured that Pearl S. Buck could never play a part in such a book: SURPRISE ! But the up-to-date timeliness is really what makes it so important . Hope one gets to read it and give to younger folk as it's lessons are vital for a proper perspective on future progeny. Wife and I already purchased and gave away to 4 couples in the 30's age group.
Some books just grip you by the throat and won't let go. This one does that. But in a nice way.I was just going to look something up that I had read about in a book review in New Scientist, and then I just couldn't stop.Incredibly interesting material, and told in a way that on top of the enjoyment and delight I feel, I also feel a sting of jealousy. Oh man how I wish I could write like that. Superior storytelling, it's at the level of, and at times surpasses that of Malcolm Gladwell due to the mastery of such an interesting area.Enjoy!From an avidly reading doctor
The science would be SO much easier to understand if accompanied by drawings and diagrams. There are NONE in this book. Well written with fascinating stories.
Many years have passed since my first lesson in genetics was a black and white movie of Theodosius Dobzhansky explaining the basics of genetics. A lot has changed since then! Carl Zimmer’s recent book She Has Her Mother’s Laugh can bring everyone up to date even if they started learning about genetics long after Dr. Dobzhansky died in 1975.Although Zimmer’s detailed telling of the story of hereditary is a wonderful read for me 3 areas were outstanding and explained clearly: 1. the obsession of European royalty with blood lines and the problems it led to as typified by the Habsburgs, 2. Epigenetics and how genes can be turned on and off, including how diet and pollutants can affect the epigenome and 3. CRISPR mechanism that enables CRISPR produced enzymes to bind to a specific DNA segment, cut it and thus shutting off the gene.Dr. Dobzhansky would find this book an enlightening read of everything that has happened since his death, I did and you will too.
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